Patient sex and its influence on general anaesthesia. Females in clinical studies: Sex differences in the clearance of CYP3A4 substrates: Sex-based differences in the effect of digoxin for the treatment of heart failure. The biology of human sex differences. Biologic and molecular mechanisms for sex differences in pharmacokinetics, pharmacodynamics and pharmacogenetics: Women encounter ADRs more often than do men.
Scientific perspectives on drug transporters and their role in drug interactions. Sex differences in the expression of hepatic drug metabolizing enzymes. Polymorphisms in human MDR1 P-glycoprotein: Variation of CYP1A2-dependent caffeine metabolism during menstrual cycle in healthy women. Transporters and drug discovery: Is gender a risk factor for adverse drug reactions? The example of drug-induced long QT syndrome. Adverse effects in women: Induction of CYP2D6 in pregnancy. Gender as a risk factor for adverse events to medications. Sex-based differences in drug activity. Women encounter ADRs more often than do men. Sex-dependent modulation of treatment response. CYP2A6 activity in a healthy Spanish population: Petersburg Pediatric University, St. Integration of hepatic drug transporters and phase II metabolizing enzymes: Obesity, sex, and acetaminophen disposition. Sex-dependent differences in cytochrome P 3A activity as assessed by midazolam disposition in humans: Quantitative prediction of intestinal metabolism in humans from a simplified intestinal availability model and empirical scaling factor. Drugs and sex differences: Petersburg neuropsychiatric research institute named after V. Sex differences in the pharmacologic effects of antiretroviral drugs: Gender differences in human pharmacokinetics and pharmacodynamics. Publication of manuscripts is fee for post-graduate students Copyright material does not necessarily reflect the views of the publisher. Sex differences in the clearance of CYP3A4 substrates: It has been established that side effects produced by drugs are more frequent in women than in men.
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